I don't want the timetables to be automatically updated in PRONOTE: how can I update them manually?

If you're working on a single base (PRONOTE base initialized with EDT data at the start of the year), make the modifications on a copy of the base (opened with EDT Single-user or commissioned with a second server in Network version). You can then manually reintegrate these modifications using the command Imports/Exports > EDT >
Import the teachers'/classes' timetables.

If you are working on two separate EDT and PRONOTE bases, perform a manual update using the command To PRONOTE > Manual transfer: generate a *PourPRONOTE.zip file, then import the modified timetables into PRONOTE using the command Imports/Exports > EDT > Recover the data. In the pop-up window, tick the box Update the timetables, the teachers' absences and replacements.